GRO-beta/MIP-2
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Product Specifications
Synonyms
Cxcl2; Mip-2; Scyb2
NCBI Gene ID
114105
UniProt
P30348
Accession Number
NP_446099
Accession Number mRNA
NM_053647
Chromosomal Location
14p22
Reactivity
Rat
Cross Reactivity
Human, Mouse, Rat
Sequence
VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.
Length
73
Form
Lyophilized
Molecular Weight
7.9 kDa
Host or Source
E. coli
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