What is the catalog number for Granzyme B?

The catalog number for Granzyme B is 103-M484.

What sizes are available for Granzyme B?

Granzyme B is available in the following size(s): 100 µg.

Is Granzyme B in stock?

Granzyme B is currently made to order / not held in immediate stock. Contact us for lead time.

Granzyme B

Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.

Product Specifications

Synonyms

Gzmb; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1/C11

NCBI Gene ID

14939

UniProt

Q3TZH4

Accession Number

NP_038570.1

Accession Number mRNA

NM_013542.2

Chromosomal Location

14 D3; 14 20.5 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Recombinant mouse protein Granzyme B

Clone

(#14G13)

Applications

WB

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.