What is the catalog number for Gp130?

The catalog number for Gp130 is 103-M531.

What sizes are available for Gp130?

Gp130 is available in the following size(s): 50 µg.

Gp130 is currently made to order / not held in immediate stock. Contact us for lead time.

Gp130

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

Product Specifications

Synonyms

Il6st; CD130; gp130; AA389424; BB405851; D13Ertd699e; 5133400A03Rik

NCBI Gene ID

16195

UniProt

Q00560

Accession Number

NP_034690.3

Accession Number mRNA

NM_010560.3

Chromosomal Location

13 D2.2; 13 67.0 cM

Reactivity

Anti-Mouse

Target Antigen

Recombinant mouse GP130

Clone

(#5R33)

Applications

WB, ICC

Purification Method

Protein G/A chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.