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GMF-beta

GMF-β a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines. Recombinant human GMF-β is a 16.5 kDa globular protein containing 141 amino acid residues including one intramolecular disulfide bond.

Product Specifications

Synonyms

GMFB; GMF

NCBI Gene ID

2764

UniProt

P60983

Accession Number

NP_004115.1

Accession Number mRNA

NM_004124

Chromosomal Location

14q22.2

Reactivity

Human

Cross Reactivity

Human

Sequence

SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Data not available.

Length

141

Form

Lyophilized

Molecular Weight

16.5 kDa

Host or Source

E. coli

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