GMF-beta
GMF-β a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines. Recombinant human GMF-β is a 16.5 kDa globular protein containing 141 amino acid residues including one intramolecular disulfide bond.
Product Specifications
Synonyms
GMFB; GMF
NCBI Gene ID
2764
UniProt
P60983
Accession Number
NP_004115.1
Accession Number mRNA
NM_004124
Chromosomal Location
14q22.2
Reactivity
Human
Cross Reactivity
Human
Sequence
SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Data not available.
Length
141
Form
Lyophilized
Molecular Weight
16.5 kDa
Host or Source
E. coli
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