GM-CSFR alpha

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.

Product Specifications

Synonyms

Csf2ra; CD116; Csfgmra; GM-CSFR; GM-CSF-Ra

NCBI Gene ID

12982

UniProt

P15509

Accession Number

NP_006131.1

Accession Number mRNA

NM_006140.4

Chromosomal Location

19 D3; 19 51.0 cM

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human GM-CSF R alpha EC domain

Clone

(#8W1)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.