What is the catalog number for GM-CSF?

The catalog number for GM-CSF is M30-012.

What sizes are available for GM-CSF?

GM-CSF is available in the following size(s): 10 µg.

GM-CSF is currently made to order / not held in immediate stock. Contact us for lead time.

GM-CSF

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 124 amino acids residues.

Product Specifications

Synonyms

Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM

NCBI Gene ID

12981

UniProt

P01587

Accession Number

NP_034099.2

Accession Number mRNA

NM_009969.4

Chromosomal Location

11 B1.3; 11 29.5 cM

Reactivity

Mouse

Cross Reactivity

Mouse

Sequence

MAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLNEEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPGQK

Assay Protocol

The lyophilized mouse GM-CSF is soluble in water and most aqueous buffers. It can be reconstituted in water to a concentration of 100 µg/ml. This solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, mouse GM-CSF exerts its biological activity in the concentration range of 0.05 to 0.5ng/ml.

Endotoxin

< 0.1 ng per µg of GM-CSF

Purity

> 98% by SDS-PAGE

Bioactivity

Testing in Progress.

Length

125

Form

Lyophilized

Buffer

30 mM Tris pH8

Reconstitution

Water

Molecular Weight

14.2 kDa

Storage Conditions

The lyophilized mouse GM-CSF, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted mouse GM-CSF should be stored in working aliquots at -20°C.