G-CSFR (CD114)
Human G-CSF R is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSF R exist that differ in their transmembrane C-terminal region. Human and mouse G-CSF R are 64% identical at the aa level. G-CSF R is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.
Product Specifications
Synonyms
CSF3R; CD114; GCSFR
NCBI Gene ID
1441
UniProt
Q99062
Accession Number
NP_000751.1
Accession Number mRNA
NM_000760.3
Chromosomal Location
1p35-p34.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human G-CSF-R EC domain
Clone
(#8F44)
Applications
WB, FC, Capture Ab
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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