G-CSFR (CD114)

Human G-CSF R is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSF R exist that differ in their transmembrane C-terminal region. Human and mouse G-CSF R are 64% identical at the aa level. G-CSF R is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.

Product Specifications

Synonyms

CSF3R; CD114; GCSFR

NCBI Gene ID

1441

UniProt

Q99062

Accession Number

NP_000751.1

Accession Number mRNA

NM_000760.3

Chromosomal Location

1p35-p34.3

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human G-CSF-R EC domain

Clone

(#8F44)

Applications

WB, FC, Capture Ab

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.