Fractalkine (CX3CL1)
Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Product Specifications
Synonyms
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
NCBI Gene ID
6376
UniProt
P78423
Accession Number
NP_002987.1
Accession Number mRNA
NM_002996.3
Chromosomal Location
16q13
Reactivity
Human
Cross Reactivity
Monkey, Mouse, Rat, Human, Bacteria
Sequence
QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human T cells using a concentration range of 5.0-10.0 ng/ml.
Length
76
Form
Lyophilized
Molecular Weight
8.5 kDa
Host or Source
E. coli
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