Flt-3 Ligand
Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
Product Specifications
Synonyms
FLT3; FLK2; STK1; CD135; FLK-2
NCBI Gene ID
2323
UniProt
P49771
Accession Number
NP_001450.2
Accession Number mRNA
NM_001459.3
Chromosomal Location
19q13.3
Reactivity
Human
Cross Reactivity
Human
Sequence
TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & Coomassie stain
Bioactivity
Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 – 1 ng/mL.
Length
155
Form
Lyophilized
Molecular Weight
17.6 kDa
Host or Source
E. coli
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL503682V 500 µL Each
Spcs2 Mouse shRNA Lentiviral Particle (Locus ID 66624)
Sign In for Pricing
View Details