FGFR-3
Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
Product Specifications
Synonyms
FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX
NCBI Gene ID
2261
UniProt
P22607
Accession Number
NP_000133
Accession Number mRNA
NM_000142
Chromosomal Location
4p16.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human FGF-R3 EC domain
Clone
(#6G11)
Applications
WB, IHC (P)
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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