FGF-21
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
Product Specifications
Synonyms
Fibroblast Growth Factor-21, FGFL
NCBI Gene ID
56636
UniProt
Q9JJN1
Accession Number
NP_064397.1
Accession Number mRNA
NM_020013.4
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses
Bioactivity
Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells.
Length
182
Form
Lyophilized
Molecular Weight
20.1 kDa
Host or Source
E. coli
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