What is the catalog number for FGF-18 (Animal Free)?

The catalog number for FGF-18 (Animal Free) is 100-025S-AF.

What sizes are available for FGF-18 (Animal Free)?

FGF-18 (Animal Free) is available in the following size(s): 5 µg.

Is FGF-18 (Animal Free) in stock?

FGF-18 (Animal Free) is currently made to order / not held in immediate stock. Contact us for lead time.

FGF-18 (Animal Free)

FGF-18 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-18 derived from E.coli is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full length protein.

Product Specifications

Synonyms

FGF18; ZFGF5; FGF-18

NCBI Gene ID

8817

UniProt

O76093

Accession Number

NP_003853.1

Accession Number mRNA

NM_003862

Chromosomal Location

5q34

Reactivity

Human

Cross Reactivity

Mouse, Rat, Human

Sequence

AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR

Endotoxin

< 0.01 ng/µg of protein (< 0.1 EU/µg)

Purity

≥ 95% by SDS-PAGE gel and HPLC analyses.

Bioactivity

Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.