FGF-10
Fibroblast Growth Factor-10 (FGF-10) is a heparin binding growth factor which stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is most related to KGF/FGF-7 and is expressed during development and preferentially in adult lungs. Human FGF-10 is a 19.3 kDa protein containing 170 amino acid residues.
Product Specifications
Synonyms
FGF10; KGF2
NCBI Gene ID
2255
UniProt
O15520
Accession Number
NP_004456.1
Accession Number mRNA
NM_004465
Chromosomal Location
5p13-p12
Reactivity
Human
Cross Reactivity
Chicken, Mouse, Human
Sequence
MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Assay Protocol
The lyophilized FGF-10 should be reconstituted in water to a concentration not lower than 50 μg/ml. For long term storage we would recommend to add at least 0.1% human or bovine serum albumin.
Purity
> 95% by SDS-PAGE
Bioactivity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Length
170
Form
Lyophilized
Buffer
0.5xPBS
Reconstitution
Water
Molecular Weight
19.3 kDa
Storage Conditions
Lyophilized samples are stable for more than six months at -20°C to -70°C.
Host or Source
E. coli
N Terminal Sequence
MLGQDM
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