FGF-8
FGF-8 (FGF-8b) is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues.
Product Specifications
Synonyms
FGF8; AIGF; KAL6; FGF-8; HBGF-8
NCBI Gene ID
2253
UniProt
P55075
Accession Number
NP_149355
Accession Number mRNA
NM_033165
Chromosomal Location
10q24
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human FGF-8
Clone
(#8D24)
Applications
WB, IHC (P), N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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