FGF-7/KGF
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
Product Specifications
Synonyms
KGF
NCBI Gene ID
2252
UniProt
P21781
Accession Number
NP_002000
Accession Number mRNA
NM_002009
Chromosomal Location
15q21.2
Reactivity
Human
Cross Reactivity
Mouse, Rat, Human, Leech
Sequence
Assay Protocol
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
The expected ED50 as determined by a cell proliferation assay using 4MBr-5 cells is 0.1-15 ng/ml.
Length
163
Form
Lyophilized
Buffer
15mM Sodium Phosphate, pH 7.0 + 25mM NaCl
Reconstitution
PBS
Molecular Weight
18.9 kDa
Storage Conditions
Host or Source
E. coli
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