FGF-6
FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.
Product Specifications
Synonyms
FGF6; HST2; HBGF-6
NCBI Gene ID
2251
UniProt
P10767
Accession Number
NP_066276
Accession Number mRNA
NM_020996
Chromosomal Location
12p13
Reactivity
Human
Cross Reactivity
Human
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Length
168
Form
Lyophilized
Buffer
10 mM NaP, pH 7.2 + 50 mM NaCl
Molecular Weight
18.7 kDa
Host or Source
E. coli
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