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FGF-2 (basic)

FGF-basic or FGF-2 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.

Product Specifications

Synonyms

FGF2; BFGF; FGFB; HBGF-2

NCBI Gene ID

2247

UniProt

P09038

Accession Number

NP_001997.5

Accession Number mRNA

NM_002006.4

Chromosomal Location

4q26

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human FGF-2 (basic) (RT #300-003)

Clone

Rabbit IgG

Applications

WB

Purification Method

Protein A purified

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Bioactivity

Western Blot: Use 2-5 µg/ml

Form

Lyophilized

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Host or Source

Rabbit

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