FGF acidic

FGF acidic, also known as FGF1, ECGF, and HBGF1, is a 17 kDa non-glycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. Alternate splicing generates a truncated isoform of human FGF acidic that consists of the N-terminal 40% of the molecule and functions as a receptor antagonist.

Product Specifications

Synonyms

FGF2; BFGF; FGFB; HBGF-2

NCBI Gene ID

2246

UniProt

P05230

Accession Number

NP_000791.1

Accession Number mRNA

NM_000800.4

Chromosomal Location

5q31

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human FGF-acidic

Clone

(#6A34)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.