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Fc gamma RII

F cγ RII, also named CD32, is a lowaffinity receptor for the Fc region of complexed IgG. Three genes for human Fcγ RII (A, B and C) and one for mouse (Fcγ RIIB), encoding type I transmembrane proteins, have been identified. The extracellular domain of mouse Fcγ RII shares approximately 95% amino acid sequence identity with that of mouse Fcγ RIII/CD16.

Product Specifications

Synonyms

Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB (Fc-gamma RII; Fc-gamma-RIIB; FcRII), IgG Fc receptor II beta, Lymphocyte antigen 17 (Ly-17)

NCBI Gene ID

14130

UniProt

P08101

Accession Number

NP_034317.1

Accession Number mRNA

NM_01087.2

Reactivity

Anti-Mouse

Target Antigen

Recombinant mouse Fc gamma RIIb

Clone

(#8N32)

Applications

WB, FC

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG2

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