Epiregulin

Epiregulin is a member of the EGF family of growth factors which includes, among others, Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF) alpha, Amphiregulin (ARG), HB (heparin-binding), EGF, Betacellulin, and the various Heregulins. They are all synthesized as transmembrane precursors and converted to soluble forms by proteolytic cleavage. Epiregulin was originally purified from the mouse fibroblast-derived tumor cell line NIH3T3/T7 (1) .

Product Specifications

Synonyms

Proepiregulin, Epiregulin (EPR)

NCBI Gene ID

13874

UniProt

Q61521

Accession Number

NP_031976.1

Accession Number mRNA

NM_007950.2

Reactivity

Anti-Mouse

Target Antigen

Mouse recombinant protein Epiregulin

Clone

(#6H12)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.