Endomucin
Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.
Product Specifications
Synonyms
Endomucin-2; Gastric cancer antigen Ga34; Mucin-14
NCBI Gene ID
51705
UniProt
Q9ULC0
Accession Number
NP_001153166.1
Accession Number mRNA
NM_001159694.1
Chromosomal Location
4q24
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human soluble Endomucin (RT #S01-064)
Clone
Rabbit IgG
Applications
WB
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 1-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Rabbit
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