What is the catalog number for EGF?

The catalog number for EGF is M10-002.

What sizes are available for EGF?

EGF is available in the following size(s): 100 µg.

EGF is currently made to order / not held in immediate stock. Contact us for lead time.

EGF

Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor) . Recombinant murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.

Product Specifications

Synonyms

Epidermal growth factor; Egf; AI790464

NCBI Gene ID

13645

UniProt

P01132

Accession Number

NP_034243.2

Accession Number mRNA

NM_010113.3

Chromosomal Location

3 G3; 3 65.2 cM

Reactivity

Mouse

Cross Reactivity

Human, Mouse, Rat

Sequence

NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.