EGF (Animal Free)
EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor) . Recombinant Human EGF is a 6.2 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.
Product Specifications
Synonyms
Epidermal growth factor; EGF; URG; HOMG4; Urogastrone
NCBI Gene ID
1950
UniProt
P01133
Accession Number
NP_001954.2
Accession Number mRNA
NM_1963.4
Chromosomal Location
4q25
Reactivity
Human
Cross Reactivity
Chicken, Cow, Dog, Hamster, Horse, Human, Human + Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Salamander, Snake, Tunicate, Zebra Fish
Sequence
NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Length
53
Form
Lyophilized
Molecular Weight
6.2 kDa
Host or Source
E. coli
Frequently Asked Questions
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