DRAK2

STK17B (also known as DRAK2) is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis. STK17B is selectively important for T-cell survival and inhibition of STK17B has therapeutic potential for autoimmune disease. T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of STK17B can affect autoimmune disease susceptibility without generalized suppression of the immune system.

Product Specifications

Synonyms

Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2

NCBI Gene ID

9262

UniProt

O94768

Accession Number

NP_004217.1

Accession Number mRNA

NM_004226.3

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human DRAK2

Clone

(#4U29)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.