DRAK2
STK17B (also known as DRAK2) is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis. STK17B is selectively important for T-cell survival and inhibition of STK17B has therapeutic potential for autoimmune disease. T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of STK17B can affect autoimmune disease susceptibility without generalized suppression of the immune system.
Product Specifications
Synonyms
Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2
NCBI Gene ID
9262
UniProt
O94768
Accession Number
NP_004217.1
Accession Number mRNA
NM_004226.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human DRAK2
Clone
(#4U29)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
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