Cystatin C
Cystatin C is a member of family 2 of the cystatin superfamily. It inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu 68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage.
Product Specifications
Synonyms
Cst3; CysC
NCBI Gene ID
13010
UniProt
P21460
Accession Number
NP_034106.2
Accession Number mRNA
NM_009976.3
Chromosomal Location
2 G3; 2 84.0 Cm
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant Cystatin C
Clone
(#4E59)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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