CXCL16
CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal mucin-like stalk sequence. The extracellular domain contains 89 amino acid residues (86 a.a. residues for the murine homolog) . Recombinant murine CXCL16 is a 9.9 kDa protein containing 88 amino acid residues.
Product Specifications
Synonyms
Cxcl16; SR-PSOX; Zmynd15; AV290116; BB024863; CXCL16v1; CXCL16v2; 0910001K24Rik
NCBI Gene ID
66102
UniProt
Q8BSU2
Accession Number
NP_075647
Accession Number mRNA
NM_023158
Chromosomal Location
11; 11 B4
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract murine lymphocytes using a concentration of 20-1000 ng/ml.
Length
88
Form
Lyophilized
Molecular Weight
9.9 kDa
Host or Source
E. coli
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