CXCL12 (SDF-1)

SDF-1α and β or CXCL12 are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues.

Product Specifications

Synonyms

CXCL12; IRH; PBSF; SDF1; TLSF; SDF1A; SDF1B; TPAR1; SCYB12

NCBI Gene ID

6387

UniProt

P48061

Accession Number

NP_954637.1

Accession Number mRNA

NM_199168.3

Chromosomal Location

10q11.1

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant CXCL12

Clone

(#9N61)

Applications

WB, IHC, FC, Capture Ab

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.