CXCL11 (I-TAC)
NAP-2 or CXCL7 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP) . NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ELR motif common to CXC chemokines that bind to CXCR1 and CXCR2.
Product Specifications
Synonyms
CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B
NCBI Gene ID
6373
UniProt
O14625
Accession Number
NP_005400.1
Accession Number mRNA
NM_005409.4
Chromosomal Location
4q21.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CXCL11
Clone
(#9N26)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
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