CXCL11 (I-TAC)

NAP-2 or CXCL7 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP) . NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ELR motif common to CXC chemokines that bind to CXCR1 and CXCR2.

Product Specifications

Synonyms

CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B

NCBI Gene ID

6373

UniProt

O14625

Accession Number

NP_005400.1

Accession Number mRNA

NM_005409.4

Chromosomal Location

4q21.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant CXCL11

Clone

(#9N26)

Applications

WB, N

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.