CXCL1 (GRO alpha)

Cotton rat growth-regulatedprotein (GRO) is a member of the ELR+ CXC subfamily of chemokines. The cotton rat GRO cDNA encodes a 100 amino acid (aa) precursor protein with a 27 aa putative signal peptide and a 73 aa mature protein. The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts.

Product Specifications

Synonyms

CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a

NCBI Gene ID

2919

UniProt

P09341

Accession Number

NP_001502.1

Accession Number mRNA

NM_001511.2

Chromosomal Location

4q21

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant CXCL1

Clone

(#9A18)

Applications

WB, N

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.