CTGFL
CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.8 kDa protein of 228 amino acid residues.
Product Specifications
Synonyms
WISP2; CCN5; CT58; CTGF-L
NCBI Gene ID
8839
UniProt
O76076
Accession Number
NP_003872
Accession Number mRNA
NM_003881
Chromosomal Location
20q13.12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human CTGFL/WISP-2
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
Host or Source
Rabbit
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