CTGFL

CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.8 kDa protein of 228 amino acid residues.

Product Specifications

Synonyms

WISP2; CCN5; CT58; CTGF-L

NCBI Gene ID

8839

UniProt

O76076

Accession Number

NP_003872

Accession Number mRNA

NM_003881

Chromosomal Location

20q13.12

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant Human CTGFL/WISP-2

Clone

Rabbit IgG

Applications

ELISA, WB

Purification Method

Antigen-affinity purified

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.