Cripto-1
Cripto, also known as TDGF-1 (Teratocarcinoma-Derived Growth Factor), is the founding member of the Epidermal Growth Factor-Cripto-1/FRL1/Cryptic Protein family of signaling proteins that function in cancer and various developmental processes. Mouse Cripto shares 66% and 34% amino acid identity with human Cripto and zebrafish one-eyed pinhead (OEP), respectively. Genetic evidence from mice and zebrafish points to a role for Cripto as an essential cofactor in Nodal signaling.
Product Specifications
Synonyms
TDGF1; CR; CRGF; CRIPTO
NCBI Gene ID
6997
UniProt
P13385
Accession Number
NP_003203.1
Accession Number mRNA
NM_003212.3
Chromosomal Location
3p21.31
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Cripto-1
Clone
(#6M17)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG1
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