CRIM1
CRIM1, also known as cysteine rich motor neuron 1, is a type I transmembrane glycoprotein containing an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 CRRs are similar to those in the BMP-binding antagonists such as Chordin. CRIM1 can interact with TGF-beta family ligands to modulate TGF-beta family ligand functions.
Product Specifications
Synonyms
CRIM1; S52; CRIM-1
NCBI Gene ID
51232
UniProt
Q9NZV1
Accession Number
NP_057525.1
Accession Number mRNA
NM_016441.2
Chromosomal Location
2p21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant CRIM1 EC domain
Clone
(#16G1)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1
Frequently Asked Questions
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