CNTF R alpha
The high-affinity CNTF receptor complex, which mediates the biological action of CNTF, contains the ligand-binding alpha subunit (CNTF R alpha) and two signal-transducing proteins, LIF R beta and gp130. Whereas LIF R beta and gp130 are widely expressed in many cell types, the expression of CNTF R alpha is restricted to the central and peripheral nervous systems. cDNAs encoding CNTF R alpha isolated from both human and rat share 96% amino acid sequence identity.
Product Specifications
Synonyms
CNTFR
NCBI Gene ID
1271
UniProt
P26992
Accession Number
NP_671693.1
Accession Number mRNA
NM_147164.2
Chromosomal Location
9p13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CNTF R-alpha
Clone
(#10L29)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
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