CNTF (Animal Free)
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Rat CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.
Product Specifications
Synonyms
Cntf
NCBI Gene ID
25707
UniProt
P20294
Accession Number
NP_037298.1
Accession Number mRNA
NM_013166.1
Chromosomal Location
1q43
Reactivity
Rat
Cross Reactivity
Frog, Human, Mouse, Rat
Sequence
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by its ability to stimulate proliferation of human TF-1 cells using a concentration range of 25.0-35.0 ng/ml.
Length
199
Form
Lyophilized
Molecular Weight
22.7 kDa
Host or Source
E. coli
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