Cerberus-1
Cerberus 1, also called DAND4, is a member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus; DAND3), and COCO/Dante (DAND5) . DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. Cerberus-S, which is generated by proteolysis in Xenopus, is a short version of the molecule and includes the C-terminal cysteine knot domain.
Product Specifications
Synonyms
CER1; DAND4
NCBI Gene ID
9350
UniProt
O95813
Accession Number
NP_005445.1
Accession Number mRNA
NM_005454.2
Chromosomal Location
9p23-p22
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Cerberus-1
Clone
(#4K48)
Applications
WB, IHC (P)
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Host or Source
Mouse
Isotype
IgG2
Frequently Asked Questions
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