CEACAM-1 (D1-4)

Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.

Product Specifications

Synonyms

CEACAM1; BGP; BGP1; BGPI, CD66a

NCBI Gene ID

634

UniProt

P13688

Accession Number

NP_001192273.1

Accession Number mRNA

NM_001205344

Chromosomal Location

19q13.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human sCEA-1 (D1-4)

Clone

Rabbit IgG

Applications

E, WB, FC

Purification Method

Protein A purified

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Bioactivity

Western Blot: Use 2-5 µg/ml

Form

Lyophilized

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.