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CD66a (CEACAM-1)

Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.

Product Specifications

Synonyms

CEACAM1; BGP; BGP1; BGPI, CD66a

NCBI Gene ID

634

UniProt

P13688

Accession Number

NP_001192273.1

Accession Number mRNA

NM_001205344

Chromosomal Location

19q13.2

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant Human CEACAM-1 (CD66a)

Clone

(#28T25)

Applications

WB, IHC, Capture Ab

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

Host or Source

Mouse

Isotype

IgG1

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