CD200

CD200 antigen, also known as OX-2, is a type I transmembrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short (19 aa) cytoplasmic tail. At least two alternate splice isoforms exist that differ in their cytoplasmic domains. CD200 is widely expressed in multiple cell types. It interacts with CD200 R1, another Ig superfamily inhibitory receptor primarily expressed on leukocytes of the myeloid lineage, to inhibit myeloid functions.

Product Specifications

Synonyms

CD200; MRC; MOX1; MOX2; OX-2

NCBI Gene ID

4345

UniProt

P41217

Accession Number

NP_005935.4

Accession Number mRNA

NM_005944

Chromosomal Location

3q 12-q13

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Human recombinant CD200

Clone

(#2N59)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.