CD31/PECAM-1, Antagonistic
The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions, on T cell subsets, and to a lesser extent, on platelets and most leukocytes. CD31 is required for the transendothelial migration of leukocytes through the intercellular spaces between vascular endothelial cells. This is a blocking antibody.
Product Specifications
Synonyms
PECAM-1
NCBI Gene ID
18613
UniProt
Q08481
Accession Number
NP_032842.2
Accession Number mRNA
NM_008816.2
Chromosomal Location
11E1; 11
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse endothelial membrane protein
Clone
(#2A14)
Applications
Inhibition
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge the vial prior to opening. Reconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2a
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