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CD31/PECAM-1, Antagonistic

The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions, on T cell subsets, and to a lesser extent, on platelets and most leukocytes. CD31 is required for the transendothelial migration of leukocytes through the intercellular spaces between vascular endothelial cells. This is a blocking antibody.

Product Specifications

Synonyms

PECAM-1

NCBI Gene ID

18613

UniProt

Q08481

Accession Number

NP_032842.2

Accession Number mRNA

NM_008816.2

Chromosomal Location

11E1; 11

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

Mouse endothelial membrane protein

Clone

(#2A14)

Applications

Inhibition

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge the vial prior to opening. Reconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS (sterile)

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Host or Source

Rat

Isotype

IgG2a

Frequently Asked Questions

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