CD26
Dipeptidyl peptidase IV (DPPIV/CD26) is a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides. It plays an important role in T-cell costimulation, chemokine biology, type II diabetes and tumor biology. There are at least 15 DPPIV-related human genes. Some function as enzymes, including DPP8, DPP9, fibroblast activation protein (FAP), prolyl endopeptidase (PREP), and N-acylaminoacyl-peptide hydrolase (APEH) while others (DPP6/DPPX and DPP10/DPRP3) may have lost their protease properties but acquired novel functions. For example, DPP6 is a critical component of neuronal A-type K+ channels.
Product Specifications
Synonyms
Dpp4; Cd26; THAM; Dpp-4
NCBI Gene ID
13482
UniProt
P28843
Accession Number
NP_034204.1
Accession Number mRNA
NM_010074.3
Chromosomal Location
2 C2-D; 2 35.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse CD26
Clone
(#9J28)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Host or Source
Rat
Isotype
IgG2
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