CCL-26 (Eotaxin-3)

Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Product Specifications

Synonyms

CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha

NCBI Gene ID

10344

UniProt

Q9Y258

Accession Number

NP_006063

Accession Number mRNA

NM_006072

Chromosomal Location

7q11.23

Reactivity

Anti-Human

Cross Reactivity

Human

Target Antigen

Recombinant human CCL-26

Clone

(#8D34)

Applications

Purification Method

Protein G chromatography

Assay Protocol

Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Form

Lyophilized

Buffer

PBS

Reconstitution

PBS

Storage Conditions

Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.