CC Chemokine Receptor D6
The D6 heptahelical membrane protein, expressed by lymphatic endothelial cells, is able to bind with high affinity to multiple proinflammatory CC chemokines. However, this binding does not allow D6 to couple to the signaling pathways activated by typical chemokine receptors such as CC-chemokine receptor-5 (CCR5) .
Product Specifications
Synonyms
ACKR2, Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9
NCBI Gene ID
1238
UniProt
O00590
Accession Number
NP_001287.2
Accession Number mRNA
NM_001296.4
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human CC Chemokine Receptor D6
Clone
(#25G14)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2
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