C-10

Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recomb

Product Specifications

Synonyms

Grcc10; PME; ULD; CST6; EPM1; STFB; EPM1A

NCBI Gene ID

14790

UniProt

O35127

Accession Number

NP_038563.1

Accession Number mRNA

NM_013535.1

Chromosomal Location

6 F2; 6 60.22 cM

Reactivity

Anti-Mouse

Cross Reactivity

Mouse

Target Antigen

E.coli derived Recombinant Murine C10 (CCL6)

Clone

Rabbit IgG

Applications

ELISA, WB

Purification Method

Antigen-affinity purified

Assay Protocol

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Form

Lyophilized from PBS

Buffer

PBS

Reconstitution

Water

Storage Conditions

The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.