Apo-SAA1
Recombinant human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL) . The level of Apo-SAA usually is 1-5 μg/ml in plasma. It increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. The human SAA gene codes for a 122 amino acid non-glycosylated polypeptide, which contains an 18 amino acid N-terminal sequence.
Product Specifications
Synonyms
Apo-SAA1
NCBI Gene ID
6288
UniProt
P0DJI8
Accession Number
NP_000322.2
Accession Number mRNA
NM_000331.4
Reactivity
Human
Cross Reactivity
Human
Sequence
MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Length
105
Form
Lyophilized
Molecular Weight
~11.7 kDa
Host or Source
E. coli
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