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Apo-SAA1

Recombinant human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues. Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL) . The level of Apo-SAA usually is 1-5 μg/ml in plasma. It increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apo-lipoprotein. The human SAA gene codes for a 122 amino acid non-glycosylated polypeptide, which contains an 18 amino acid N-terminal sequence.

Product Specifications

Synonyms

Apo-SAA1

NCBI Gene ID

6288

UniProt

P0DJI8

Accession Number

NP_000322.2

Accession Number mRNA

NM_000331.4

Reactivity

Human

Cross Reactivity

Human

Sequence

MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

Length

105

Form

Lyophilized

Molecular Weight

~11.7 kDa

Host or Source

E. coli

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