What is the catalog number for α-MSH?

The catalog number for α-MSH is HY-P0252.

What sizes are available for α-MSH?

α-MSH is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does α-MSH come in?

α-MSH is available in 4 different pack sizes.

α-MSH is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures α-MSH?

α-MSH is manufactured by QuantiMol.

What is the estimated delivery time for α-MSH?

Estimated delivery time for α-MSH is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for α-MSH?

The safety data sheet for α-MSH is available here: http://file.medchemexpress.com/batch_PDF/HY-P0252/α-MSH-SDS-MedChemExpress.pdf.

α-MSH

α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) [1][2].

Product Specifications

CAS Number

581-05-5

Product Name Alternative

α-Melanocyte-Stimulating Hormone

UNSPSC

12352209

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/_alpha_-Melanocyte-Stimulating_Hormone__MSH_,_amide.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 12.5 mg/mL

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC(C)=O)=O)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)C(C)C)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C77H109N21O19S

Molecular Weight

1664.88

References & Citations

[1]Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55 (5) :1920-9.|[2]M S Kim, et al. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes. 2000 Feb;49 (2) :177-82.|[3]Lipton JM, et al. Mechanisms of antiinflammatory action of alpha-MSH peptides. In vivo and in vitro evidence. Ann N Y Acad Sci. 1999;885:173-182.