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Medroxyprogesterone acetate

Product Specifications

UNSPSC Description

Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

Target Antigen

Androgen Receptor; Endogenous Metabolite; Glucocorticoid Receptor; Progesterone Receptor

Type

Natural Products

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Medroxyprogesterone-acetate.html

Purity

99.88

Solubility

DMSO : 10 mg/mL (ultrasonic)|Ethanol : 6.25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL

Smiles

CC(O[C@@]([C@]12C)(CC[C@@]1([H])[C@@](C[C@H](C)C3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC2)C(C)=O)=O

Molecular Weight

386.52

References & Citations

[1]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80.|[2]Simoncini T, et al. Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells. Endocrinology. 2004 Dec;145(12):5745-56. |[3]Smith D, et al. Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat. Biopharm Drug Dispos. 1993 May;14(4):341-55. |[4]Bernardi F, et al. Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels. Neuroendocrinology. 2006;83(5-6):348-59.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B0469/Medroxyprogesterone-acetate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B0469/Medroxyprogesterone-acetate-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

71-58-9

Available Sizes

Curated Selection

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